We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Adipocytes as regulators of energy balance and glucose homeostasis.
- Authors
Rosen, Evan D; Spiegelman, Bruce M
- Abstract
Adipocytes have been studied with increasing intensity as a result of the emergence of obesity as a serious public health problem and the realization that adipose tissue serves as an integrator of various physiological pathways. In particular, their role in calorie storage makes adipocytes well suited to the regulation of energy balance. Adipose tissue also serves as a crucial integrator of glucose homeostasis. Knowledge of adipocyte biology is therefore crucial for understanding the pathophysiological basis of obesity and metabolic diseases such as type 2 diabetes. Furthermore, the rational manipulation of adipose physiology is a promising avenue for therapy of these conditions.
- Publication
Nature, 2006, Vol 444, Issue 7121, p847
- ISSN
1476-4687
- Publication type
Journal Article
- DOI
10.1038/nature05483