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- Title
Hepatitis C and liver transplantation.
- Authors
Brown, Robert S
- Abstract
Liver transplantation is a life-saving therapy to correct liver failure, portal hypertension and hepatocellular carcinoma arising from hepatitis C infection. But despite the successful use of living donors and improvements in immunosuppression and antiviral therapy, organ demand continues to outstrip supply and recurrent hepatitis C with accelerated progression to cirrhosis of the graft is a frequent cause of graft loss and the need for retransplantation. Appropriate selection of candidates and timing of transplantation, coupled with better pre- and post-transplant antiviral therapy, are needed to improve outcomes.
- Publication
Nature, 2005, Vol 436, Issue 7053, p973
- ISSN
1476-4687
- Publication type
Journal Article
- DOI
10.1038/nature04083