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Title
Somatic cell nuclear transfer.
Authors
Wilmut, I; Beaujean, N; de Sousa, P A; Dinnyes, A; King, T J; Paterson, L A; Wells, D N; Young, L E
Abstract
Cloning by nuclear transfer from adult somatic cells is a remarkable demonstration of developmental plasticity. When a nucleus is placed in oocyte cytoplasm, the changes in chromatin structure that govern differentiation can be reversed, and the nucleus can be made to control development to term.