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- Title
Structural basis for the recognition of hydroxyproline in HIF-1 α by pVHL.
- Authors
Wai-Ching Hon; Wilson, Michael I.; Harlos, Karl; Claridge, Timothy D.W.; Schofield, Christopher J.; Pugh, Christopher W.; Maxwell, Patrick H.; Ratcliffe, Peter J.; Stuart, David I.; Jones, E. Yvonne
- Abstract
Details a study which examined the structural basis for the relationship between protein of the von Hippel-Lindau tumor (pVHL) suppressor gene and hypoxia-inducible factor-1 (HIF-1) transcriptional complex. Physiological significance of pVHL and HIF-1; Mechanism of action of pVHL and HIF-1; Methodology and results.
- Publication
Nature, 2002, Vol 417, Issue 6892, p975
- ISSN
0028-0836
- Publication type
Academic Journal
- DOI
10.1038/nature00767