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- Title
Diversity in cell surface sialic acid presentations: implications for biology and disease.
- Authors
Varki, Nissi M; Varki, Ajit
- Abstract
Sialic acids (Sias) are typically found as terminal monosaccharides attached to cell surface glycoconjugates. They play many important roles in many physiological and pathological processes, including microbe binding that leads to infections, regulation of the immune response, the progression and spread of human malignancies and in certain aspects of human evolution. This review will provide some examples of these diverse roles of Sias and briefly address immunohistochemical approaches to their detection.
- Publication
Laboratory investigation; a journal of technical methods and pathology, 2007, Vol 87, Issue 9, p851
- ISSN
0023-6837
- Publication type
Journal Article
- DOI
10.1038/labinvest.3700656