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- Title
Pancreatic steatosis: harbinger of type 2 diabetes in obese rodents.
- Authors
Lee, Y; Lingvay, I; Szczepaniak, L S; Ravazzola, M; Orci, L; Unger, R H
- Abstract
The aim of this study was to determine if the fat accumulation in the exocrine pancreas fat of obese Zucker diabetic fatty (ZDF) rodents, like that in their endocrine pancreas, precedes the onset of type 2 diabetes mellitus (T2DM). As the fat content of whole pancreas, but not islets, can now be measured in humans by magnetic resonance spectroscopy (MRS), such measurements could be used as a predictor of impending T2DM and an indication for preventive intervention.
- Publication
International journal of obesity (2005), 2010, Vol 34, Issue 2, p396
- ISSN
1476-5497
- Publication type
Journal Article
- DOI
10.1038/ijo.2009.245