We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Genetic subtype differences in neural circuitry of food motivation in Prader-Willi syndrome.
- Authors
Holsen, L M; Zarcone, J R; Chambers, R; Butler, M G; Bittel, D C; Brooks, W M; Thompson, T I; Savage, C R
- Abstract
Differences in behavioral phenotypes between the two most common subtypes of Prader-Willi syndrome (PWS) (chromosome 15q deletions and maternal uniparental disomy 15 (UPD) indicate that distinct neural networks may be affected. Though both subtypes display hyperphagia, the deletion subgroup shows reduced behavioral inhibition around food, whereas those with UPD are generally more able to maintain cognitive control over food intake impulses.
- Publication
International journal of obesity (2005), 2009, Vol 33, Issue 2, p273
- ISSN
1476-5497
- Publication type
Journal Article
- DOI
10.1038/ijo.2008.255