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- Title
Cough in pediatric patients receiving angiotensin-converting enzyme inhibitor therapy or angiotensin receptor blocker therapy in randomized controlled trials.
- Authors
Baker-Smith, C M; Benjamin, D K, Jr; Califf, R M; Murphy, M D; Li, J S; Smith, P B
- Abstract
The incidence of cough in children receiving antihypertension therapy with angiotensin-converting enzyme inhibitors (ACEis) or angiotensin receptor blockers (ARBs) is unknown. We analyzed patient-level data from eight randomized trials for the treatment of pediatric hypertension, six of them involving ACEis and two involving ARBs. The incidence of cough in children receiving ACEis (reported cough, 3.2%) was similar to that in children receiving ARBs (reported cough, 1.8%) (P = 0.34). Reports of cough were lower in children than in adults.
- Publication
Clinical pharmacology and therapeutics, 2010, Vol 87, Issue 6, p668
- ISSN
1532-6535
- Publication type
Journal Article
- DOI
10.1038/clpt.2009.231