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- Title
The pharmacogenomics of membrane transporters project: research at the interface of genomics and transporter pharmacology.
- Authors
Kroetz, D L; Yee, S W; Giacomini, K M
- Abstract
Since the cloning of the first membrane transporter, our understanding of the role of transporters in clinical drug disposition and response has grown enormously. In parallel, large-scale genome-wide variation studies and the emerging field of pharmacogenomics have ushered in a new understanding of variations in drug response. At the crossroads of pharmacogenomics and transporter biology is the National Institutes of Health-funded Pharmacogenomics of Membrane Transporters (PMT) project, centered at the University of California, San Francisco.
- Publication
Clinical pharmacology and therapeutics, 2010, Vol 87, Issue 1, p109
- ISSN
1532-6535
- Publication type
Journal Article
- DOI
10.1038/clpt.2009.226