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Title
Genistein downregulates onco-miR-1260b and inhibits Wnt-signalling in renal cancer cells.
Authors
Hirata, H; Ueno, K; Nakajima, K; Tabatabai, Z L; Hinoda, Y; Ishii, N; Dahiya, R
Abstract
Wnt-signalling has an important role in renal cancer and it is modulated by genistein in other cancers. Recently, microRNAs (miRNAs) have emerged as new regulators of gene expression. Thus, we focused on miRNAs to examine the regulatory mechanism of genistein on the Wnt-signalling pathway in renal cell carcinoma (RCC).
Publication
British journal of cancer, 2013, Vol 108, Issue 10, p2070