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Title
The cost-effectiveness of screening lung cancer patients for targeted drug sensitivity markers.
Authors
Atherly, A J; Camidge, D R
Abstract
New oncology drugs are being developed in conjunction with companion diagnostics with approval restricting their use to certain biomarker-positive subgroups. We examined the impact of different predictive biomarker screening techniques and population enrichment criteria on the cost-effectiveness of targeted drugs in lung cancer, using ALK and crizotinib to build the initial model.
Publication
British journal of cancer, 2012, Vol 106, Issue 6, p1100