We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
MicroRNA profiling of diagnostic needle aspirates from patients with pancreatic cancer.
- Authors
Ali, S; Saleh, H; Sethi, S; Sarkar, F H; Philip, P A
- Abstract
A major challenge to the development of biomarkers for pancreatic cancer (PC) is the small amount of tissue obtained at the time of diagnosis. Single-gene analyses may not reliably predict biology of PC because of its complex molecular makeup. MicroRNA (miRNA) profiling may provide a more informative molecular interrogation of tumours. The primary objective of this study was to determine the feasibility of performing miRNA arrays and quantitative real-time PCR (qRT-PCR) from archival formalin-fixed paraffin-embedded (FFPE) cell blocks obtained from fine-needle aspirates (FNAs) that is the commonest diagnostic procedure for suspected PC.
- Publication
British journal of cancer, 2012, Vol 107, Issue 8, p1354
- ISSN
1532-1827
- Publication type
Journal Article
- DOI
10.1038/bjc.2012.383