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- Title
Combined effect of ALK and MEK inhibitors in EML4-ALK-positive non-small-cell lung cancer cells.
- Authors
Tanizaki, J; Okamoto, I; Takezawa, K; Sakai, K; Azuma, K; Kuwata, K; Yamaguchi, H; Hatashita, E; Nishio, K; Janne, P A; Nakagawa, K
- Abstract
Although most non-small-cell lung cancer (NSCLC) patients with the echinoderm microtubule-associated protein-like 4 (EML4) - anaplastic lymphoma kinase (ALK) fusion gene - benefit from ALK tyrosine kinase inhibitors (ALK-TKIs), the efficacy of these drugs varies greatly among individuals.
- Publication
British journal of cancer, 2012, Vol 106, Issue 4, p763
- ISSN
1532-1827
- Publication type
Journal Article
- DOI
10.1038/bjc.2011.586