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- Title
Serum and colonic mucosal immune markers in irritable bowel syndrome.
- Authors
Chang, Lin; Adeyemo, Mopelola; Karagiannides, Iordanis; Videlock, Elizabeth J; Bowe, Collin; Shih, Wendy; Presson, Angela P; Yuan, Pu-Qing; Cortina, Galen; Gong, Hua; Singh, Sharat; Licudine, Arlene; Mayer, Minou; Tache, Yvette; Pothoulakis, Charalabos; Mayer, Emeran A
- Abstract
Low-grade colonic mucosal inflammation has been postulated to have an important role in the pathophysiology of irritable bowel syndrome (IBS). The objectives of this study were (i) to identify serum and tissue-based immunological and neuroendocrine markers associated with mucosal inflammation in male (M) and female (F) patients with non-post-infectious IBS (non-PI-IBS) compared with healthy controls and (ii) to assess possible correlations of such markers with IBS symptoms.
- Publication
The American journal of gastroenterology, 2012, Vol 107, Issue 2, p262
- ISSN
1572-0241
- Publication type
Journal Article
- DOI
10.1038/ajg.2011.423