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- Title
Serum miR-122 as a biomarker of necroinflammation in patients with chronic hepatitis C virus infection.
- Authors
Bihrer, Verena; Friedrich-Rust, Mireen; Kronenberger, Bernd; Forestier, Nicole; Haupenthal, Jörg; Shi, Ying; Peveling-Oberhag, Jan; Radeke, Heinfried H; Sarrazin, Christoph; Herrmann, Eva; Zeuzem, Stefan; Waidmann, Oliver; Piiper, Albrecht
- Abstract
The liver contains large amounts of microRNA-122 (miR-122), whereas other tissues contain only marginal amounts of this miRNA. MicroRNAs have also been found to circulate in the blood in a cell-free form; their potential as readily accessible disease markers is currently evaluated. Here, we investigated if the serum levels of miR-122 might be useful as disease parameter in patients with chronic hepatitis C virus (HCV) infection.
- Publication
The American journal of gastroenterology, 2011, Vol 106, Issue 9, p1663
- ISSN
1572-0241
- Publication type
Journal Article
- DOI
10.1038/ajg.2011.161