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- Title
The natural history of adult Crohn's disease in population-based cohorts.
- Authors
Peyrin-Biroulet, Laurent; Loftus, Edward V, Jr; Colombel, Jean-Frederic; Sandborn, William J
- Abstract
Natural history studies provide invaluable data on the disease course. First, they help define the end points for clinical trials that are designed to test drugs for the end point of disease modification in chronic disabling diseases. Natural history studies can also help to identify subsets of patients in whom the disease prognosis can be stratified according to clinical features. This comprehensive review summarizes our current knowledge of the natural history of Crohn's disease in adults as reported in population-based studies that include long-term follow-up results.
- Publication
The American journal of gastroenterology, 2010, Vol 105, Issue 2, p289
- ISSN
1572-0241
- Publication type
Journal Article
- DOI
10.1038/ajg.2009.579