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- Title
Candida albicans colonization and ASCA in familial Crohn's disease.
- Authors
Standaert-Vitse, Annie; Sendid, Boualem; Joossens, Marie; François, Nadine; Vandewalle-El Khoury, Peggy; Branche, Julien; Van Kruiningen, Herbert; Jouault, Thierry; Rutgeerts, Paul; Gower-Rousseau, Corinne; Libersa, Christian; Neut, Christel; Broly, Franck; Chamaillard, Mathias; Vermeire, Séverine; Poulain, Daniel; Colombel, Jean-Frédéric
- Abstract
Anti-Saccharomyces cerevisiae antibodies (ASCAs) are present in 50-60% of patients with Crohn's disease (CD) and in 20-25% of their healthy relatives (HRs). The yeast, Candida albicans, has been shown to generate ASCAs, but the presence of C. albicans in the digestive tract of CD patients and their HRs has never been investigated. Therefore, we studied C. albicans carriage in familial CD and its correlation with ASCAs.
- Publication
The American journal of gastroenterology, 2009, Vol 104, Issue 7, p1745
- ISSN
1572-0241
- Publication type
Journal Article
- DOI
10.1038/ajg.2009.225