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- Title
The safety of proton pump inhibitors (PPIs) in pregnancy: a meta-analysis.
- Authors
Gill, Simerpal K; O'Brien, Lisa; Einarson, Thomas R; Koren, Gideon
- Abstract
Heartburn and acid reflux are common medical disorders in pregnancy and can result in serious discomfort and complications. Furthermore, some pregnant women also experience more severe gastrointestinal conditions, such as Helicobacter pylori infections, peptic ulcers, and Zollinger-Ellison syndrome. To allow the use of proton pump inhibitors (PPIs) in pregnancy, the fetal safety of this drug class must be established. The aim of this study is to determine the fetal safety of PPIs during early pregnancy through systematic literature review.
- Publication
The American journal of gastroenterology, 2009, Vol 104, Issue 6, p1541
- ISSN
1572-0241
- Publication type
Journal Article
- DOI
10.1038/ajg.2009.122