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- Title
Y chromosome sequence variation and the history of human populations.
- Authors
Underhill, P A; Shen, P; Lin, A A; Jin, L; Passarino, G; Yang, W H; Kauffman, E; Bonné-Tamir, B; Bertranpetit, J; Francalacci, P; Ibrahim, M; Jenkins, T; Kidd, J R; Mehdi, S Q; Seielstad, M T; Wells, R S; Piazza, A; Davis, R W; Feldman, M W; Cavalli-Sforza, L L; Oefner, P J
- Abstract
Binary polymorphisms associated with the non-recombining region of the human Y chromosome (NRY) preserve the paternal genetic legacy of our species that has persisted to the present, permitting inference of human evolution, population affinity and demographic history. We used denaturing high-performance liquid chromatography (DHPLC; ref. 2) to identify 160 of the 166 bi-allelic and 1 tri-allelic site that formed a parsimonious genealogy of 116 haplotypes, several of which display distinct population affinities based on the analysis of 1062 globally representative individuals. A minority of contemporary East Africans and Khoisan represent the descendants of the most ancestral patrilineages of anatomically modern humans that left Africa between 35,000 and 89,000 years ago.
- Publication
Nature genetics, 2000, Vol 26, Issue 3, p358
- ISSN
1061-4036
- Publication type
Journal Article
- DOI
10.1038/81685