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- Title
Expression profiling using cDNA microarrays.
- Authors
Duggan, D J; Bittner, M; Chen, Y; Meltzer, P; Trent, J M
- Abstract
cDNA microarrays are capable of profiling gene expression patterns of tens of thousands of genes in a single experiment. DNA targets, in the form of 3' expressed sequence tags (ESTs), are arrayed onto glass slides (or membranes) and probed with fluorescent- or radioactively-labelled cDNAs. Here, we review technical aspects of cDNA microarrays, including the general principles, fabrication of the arrays, target labelling, image analysis and data extraction, management and mining.
- Publication
Nature genetics, 1999, Vol 21, Issue 1 Suppl, p10
- ISSN
1061-4036
- Publication type
Journal Article
- DOI
10.1038/4434