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- Title
Olfaction: mosquito receptor for human-sweat odorant.
- Authors
Hallem, Elissa A; Nicole Fox, A; Zwiebel, Laurence J; Carlson, John R
- Abstract
Female Anopheles mosquitoes, the world's most important vector of Plasmodium falciparum malaria, locate their human hosts primarily through olfactory cues, but the molecular mechanisms that underlie this recognition are a mystery. Here we show that the Anopheles gambiae protein AgOr1, a female-specific member of a family of putative odorant receptors, responds to a component of human sweat. Compounds designed to activate or block receptors of this type could function as attractants for trapping mosquitoes or as insect repellents in helping to control Anopheles and other insect pests.
- Publication
Nature, 2004, Vol 427, Issue 6971, p212
- ISSN
1476-4687
- Publication type
Journal Article
- DOI
10.1038/427212a