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Title
RAF/RAS oncogenes and mismatch-repair status.
Authors
Rajagopalan, Harith; Bardelli, Alberto; Lengauer, Christoph; Kinzler, Kenneth W.; Vogelstein, Bert; Velculescu, Victor E.
Abstract
Reports that activation of mutations in one RAF gene, BRAF, have been found in a high proportion of melanomas and a small fraction of other cancers. Repair of mismatched bases in DNA; Gene mutations in colorectal tumors; Mutagenesis in a repair-deficient background.