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- Title
Meiotic recombination hot spots and cold spots.
- Authors
Petes, T D
- Abstract
Meiotic recombination events are distributed unevenly throughout eukaryotic genomes. This inhomogeneity leads to distortions of genetic maps that can hinder the ability of geneticists to identify genes by map-based techniques. Various lines of evidence, particularly from studies of yeast, indicate that the distribution of recombination events might reflect, at least in part, global features of chromosome structure, such as the distribution of modified nucleosomes.
- Publication
Nature reviews. Genetics, 2001, Vol 2, Issue 5, p360
- ISSN
1471-0056
- Publication type
Journal Article
- DOI
10.1038/35072078