Your institution may have access to this item. Find your institution then sign in to continue.
Title
The many substrates and functions of ATM.
Authors
Kastan, M B; Lim, D S
Abstract
As its name suggests, the ATM--'ataxia-telangiectasia, mutated'--gene is responsible for the rare disorder ataxia-telangiectasia. Patients show various abnormalities, mainly in their responses to DNA damage, but also in other cellular processes. Although it is hard to understand how a single gene product is involved in so many physiological processes, a clear picture is starting to emerge.