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- Title
Are desmosomes more than tethers for intermediate filaments?
- Authors
Green, K J; Gaudry, C A
- Abstract
Desmosomes are intercellular adhesive junctions that anchor intermediate filaments at membrane-associated plaques in adjoining cells, thereby forming a three-dimensional supracellular scaffolding that provides tissues with mechanical strength. But desmosomes have also recently been recognized as sensors that respond to environmental and cellular cues by modulating their assembly state and, possibly, their signalling functions.
- Publication
Nature reviews. Molecular cell biology, 2000, Vol 1, Issue 3, p208
- ISSN
1471-0072
- Publication type
Journal Article
- DOI
10.1038/35043032