We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
The biochemistry of apoptosis.
- Authors
Hengartner, M O
- Abstract
Apoptosis--the regulated destruction of a cell--is a complicated process. The decision to die cannot be taken lightly, and the activity of many genes influence a cell's likelihood of activating its self-destruction programme. Once the decision is taken, proper execution of the apoptotic programme requires the coordinated activation and execution of multiple subprogrammes. Here I review the basic components of the death machinery, describe how they interact to regulate apoptosis in a coordinated manner, and discuss the main pathways that are used to activate cell death.
- Publication
Nature, 2000, Vol 407, Issue 6805, p770
- ISSN
0028-0836
- Publication type
Journal Article
- DOI
10.1038/35037710