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Title
Thrombin signalling and protease-activated receptors.
Abstract
Discusses protease-activated receptors (PAR) that helps coagulation protease thrombin regulate cellular behavior. Discussion of the receptors which provide a mechanism linking mechanical information in the form of tissue injury or vascular leakage to cellular responses; Role of PARs in haemostasis and thrombosis, inflammation, and blood vessel development; Future outlook.