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- Title
Structure of a bacterial 30S ribosomal subunit at 5.5 A resolution.
- Authors
Clemons, W M, Jr; May, J L; Wimberly, B T; McCutcheon, J P; Capel, M S; Ramakrishnan, V
- Abstract
The 30S ribosomal subunit binds messenger RNA and the anticodon stem-loop of transfer RNA during protein synthesis. A crystallographic analysis of the structure of the subunit from the bacterium Thermus thermophilus is presented. At a resolution of 5.5 A, the phosphate backbone of the ribosomal RNA is visible, as are the alpha-helices of the ribosomal proteins, enabling double-helical regions of RNA to be identified throughout the subunit, all seven of the small-subunit proteins of known crystal structure to be positioned in the electron density map, and the fold of the entire central domain of the small-subunit ribosomal RNA to be determined.
- Publication
Nature, 1999, Vol 400, Issue 6747, p833
- ISSN
0028-0836
- Publication type
Journal Article
- DOI
10.1038/23631