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Title
Structural basis for self-association and receptor recognition of human TRAF2.
Authors
Young Chul Park; Burkitt, Vicki; Villa, Anthony R.; Liang Tong; Hao Wu
Abstract
Presents research which described the crystal structure of the domain of tumor necrosis factor (TNF)-receptor-associated factors (TRAF) in human TRAF2. Role of TRAFs in signal transduction and cell metabolism; Importance of the carboxy-terminal region of TRAFs; Details about the structure; Significance of the trimeric structure of the TRAF domain.