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- Title
HIV infection affects parietal-dependent spatial cognition: evidence from mental rotation and hierarchical pattern perception.
- Authors
Olesen, Pernille J; Schendan, Haline E; Amick, Melissa M; Cronin-Golomb, Alice
- Abstract
Human immunodeficiency virus (HIV) in the asymptomatic phase of the infection impairs some aspects of cognition, but little is known about how visuospatial functions are affected. In the present study, performance on tasks of mental rotation and hierarchical pattern perception was investigated in 14 HIV-positive men and 12 age- and education-matched HIV-negative men. Processes related to mental rotation of objects and hands were impaired in HIV-positive participants as compared to the HIV-negative group. The HIV-positive group was also impaired on hierarchical pattern perception of local targets under global biasing conditions. Consistent with these results, the HIV-positive participants showed impaired performance on standard clinical neuropsychological tests of visuospatial function. These findings indicate that the detrimental effects of HIV on cognition appear even in asymptomatic individuals and affect diverse visuospatial functions that depend upon the integrity of parietal brain regions.
- Publication
Behavioral neuroscience, 2007, Vol 121, Issue 6, p1163
- ISSN
0735-7044
- Publication type
Journal Article
- DOI
10.1037/0735-7044.121.6.1163