We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Garrotes, springs, ratchets, and whips: putting dynamin models to the test.
- Authors
Sever, S; Damke, H; Schmid, S L
- Abstract
The GTPase dynamin is essential for clathrin-mediated endocytosis. Numerous new and exciting discoveries regarding dynamin function in vivo and in vitro have led to various models in which dynamin functions directly in membrane fission and the release of clathrin-coated vesicles from the plasma membrane. This would make dynamin unique among GTPases in its ability to act as a mechanochemical enzyme. Here we review the various models and their supporting data. We then discuss new findings that raise doubts as to whether dynamin breaks the paradigm that governs regulatory GTPases.
- Publication
Traffic (Copenhagen, Denmark), 2000, Vol 1, Issue 5, p385
- ISSN
1398-9219
- Publication type
Journal Article
- DOI
10.1034/j.1600-0854.2000.010503.x