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- Title
Genetic transformation in Streptococcus mutans requires a peptide secretion-like apparatus.
- Authors
Petersen, F C; Scheie, A A
- Abstract
Competence for genetic transformation in Streptococcus pneumoniae and Streptococcus gordonii involves the ComAB secretion apparatus, which is thought to export the competence-stimulating peptide. Homologous secretory systems are also used for the export of certain bacteriocins and bacteriocin-like peptides. In this study, a similar secretory apparatus was found in the Streptococcus mutans genome, and its role in transformation was investigated. Gene inactivation resulted in a mutant deficient in transformability. We suggest that secretion of a peptide, possibly the competence-stimulating peptide itself, is involved in competence induction also in S. mutans.
- Publication
Oral microbiology and immunology, 2000, Vol 15, Issue 5, p329
- ISSN
0902-0055
- Publication type
Journal Article
- DOI
10.1034/j.1399-302x.2000.150511.x