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- Title
Cellular infiltration and cytokine mRNA expression in perennial allergic rhinitis.
- Authors
Varga, E M; Jacobson, M R; Till, S J; Masuyama, K; O'Brien, F; Rak, S; Lund, V; Scadding, G K; Hamid, Q A; Durham, S R
- Abstract
Allergen challenge in allergic rhinitis patients leads to local eosinophilia and Th2-type cytokine expression. Natural exposure to grass pollen is additionally characterized by epithelial mast-cell infiltration. We hypothesized that perennial allergic rhinitis is also associated with T-cell and eosinophil infiltration of the nasal mucosa, local Th2-type cytokine expression, and increased numbers of nasal epithelial mast cells.
- Publication
Allergy, 1999, Vol 54, Issue 4, p338
- ISSN
0105-4538
- Publication type
Journal Article
- DOI
10.1034/j.1398-9995.1999.00957.x