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- Title
The spectrum of recurrent thoughts and behaviors in frontotemporal dementia.
- Authors
Mendez, Mario F; Shapira, Jill S
- Abstract
This article describes the spectrum of recurrent thoughts and behaviors that can result from frontotemporal dementia (FTD) and its variants. Although repetitive behaviors can result from a range of brain disorders, FTD is the most common neurologic cause of new-onset recurrent thoughts and behaviors in middle or late life. Patients with FTD can manifest typical or bizarre compulsions, hoarding, verbal and motor stereotypies and complex tics; self-injurious acts, perseverations; and fixed, obsessional thoughts. The frequency and variability of these repetitive behaviors suggest a common disturbance of orbitofrontal-basal ganglia circuits involved in response inhibition. The amelioration of these recurrent events with the administration of serotonin selective reuptake inhibitors further suggests a serotonergic deficit.
- Publication
CNS spectrums, 2008, Vol 13, Issue 3, p202
- ISSN
1092-8529
- Publication type
Journal Article
- DOI
10.1017/s1092852900028443