Title

Presumed Malignant Optic Glioma of Adulthood: Prolonged Survival with Temozolomide and Radiotherapy.

Authors

Tao, Brendan; Handzic, Armin; Margolin, Edward

Abstract

The article in the Canadian Journal of Neurological Sciences discusses a case of Presumed Malignant Optic Glioma of Adulthood, highlighting the challenges in diagnosis and treatment. The patient initially responded well to temozolomide and radiotherapy but later experienced rapid progression of the disease, leading to eventual demise. The article emphasizes the aggressive nature of MOGA, its potential for metastasis along the neuro-axis, and the importance of considering this diagnosis in patients with atypical optic neuritis. The study underscores the need for improved diagnostic techniques and optimal treatment strategies for managing this rare and fatal condition.

Subjects

MYELIN oligodendrocyte glycoprotein; OPTIC disc; OPTIC nerve; OPTIC neuritis; NEUROMYELITIS optica

Publication

Canadian Journal of Neurological Sciences, 2024, Vol 51, Issue 6, p888

ISSN

0317-1671

Publication type

Academic Journal

DOI

10.1017/cjn.2023.312