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- Title
A novel immunosuppressant, FTY720, induces peripheral lymphodepletion of both T- and B cells and immunosuppression in baboons.
- Authors
Quesniaux, V; Fullard, L; Arendse, H; Davison, G; Markgraaff, N; Auer, R; Ehrhart, F; Kraus, G; Schuurman, H J
- Abstract
FTY720, a new immunosuppressant active in transplantation models, modulates lymphocyte re-circulation, leading to peripheral lymphopenia and increased lymphocytes in lymph nodes and Peyer's patches. Here, we investigated the susceptibility of baboons to FTY720 as an introductory study to transplantation protocols.
- Publication
Transplant immunology, 1999, Vol 7, Issue 3, p149
- ISSN
0966-3274
- Publication type
Journal Article
- DOI
10.1016/s0966-3274(99)80034-3