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Title
Impact of sex on inheritance of ankylosing spondylitis: a cohort study.
Authors
Calin, A; Brophy, S; Blake, D
Abstract
Ankylosing spondylitis is a genetically determined and commonly familial disorder. Men and women differ in their susceptibility to ankylosing spondylitis, with about 2.5 men affected for every woman with the disease. We investigated the influence of the sex of the index case on disease penetrance within families.