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- Title
Therapeutic plasma exchange and intravenous immunoglobulin for obsessive-compulsive disorder and tic disorders in childhood.
- Authors
Perlmutter, S J; Leitman, S F; Garvey, M A; Hamburger, S; Feldman, E; Leonard, H L; Swedo, S E
- Abstract
In children, exacerbations of tics and obsessive symptoms may occur after infection with group A beta-haemolytic streptococci. If post-streptococcal autoimmunity is the cause of the exacerbations, then children might respond to immunomodulatory treatments such as plasma exchange or intravenous immunoglobulin (IVIG). We studied whether plasma exchange or IVIG would be better than placebo (sham IVIG) in reducing severity of neuropsychiatric symptoms.
- Publication
Lancet (London, England), 1999, Vol 354, Issue 9185, p1153
- ISSN
0140-6736
- Publication type
Journal Article
- DOI
10.1016/S0140-6736(98)12297-3