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- Title
Circulating concentrations of insulin-like growth factor-I and risk of breast cancer.
- Authors
Hankinson, S E; Willett, W C; Colditz, G A; Hunter, D J; Michaud, D S; Deroo, B; Rosner, B; Speizer, F E; Pollak, M
- Abstract
Insulin-like growth factor (IGF)-I, a mitogenic and antiapoptotic peptide, can affect the proliferation of breast epithelial cells, and is thought to have a role in breast cancer. We hypothesised that high circulating IGF-I concentrations would be associated with an increased risk of breast cancer.
- Publication
Lancet (London, England), 1998, Vol 351, Issue 9113, p1393
- ISSN
0140-6736
- Publication type
Journal Article
- DOI
10.1016/S0140-6736(97)10384-1