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- Title
Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis/Riluzole Study Group II.
- Authors
Lacomblez, L; Bensimon, G; Leigh, P N; Guillet, P; Meininger, V
- Abstract
Amyotrophic lateral sclerosis (ALS) is a progressive disease with no effective treatment. In an initial study, riluzole decreased mortality and slowed muscle-strength deterioration in ALS patients. We have carried out a double-blind, placebo-controlled, multicentre study to confirm those findings and to assess drug efficacy at different doses.
- Publication
Lancet (London, England), 1996, Vol 347, Issue 9013, p1425
- ISSN
0140-6736
- Publication type
Journal Article
- DOI
10.1016/s0140-6736(96)91680-3