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- Title
Randomised trial of effect of amiodarone on mortality in patients with left-ventricular dysfunction after recent myocardial infarction: EMIAT. European Myocardial Infarct Amiodarone Trial Investigators.
- Authors
Julian, D G; Camm, A J; Frangin, G; Janse, M J; Munoz, A; Schwartz, P J; Simon, P
- Abstract
Ventricular arrhythmias are a major cause of death after myocardial infarction, especially in patients with poor left-ventricular function. Previous attempts to identify and suppress arrhythmias with various antiarrhythmic drugs failed to reduce or actually increase mortality. Amiodarone is a powerful antiarrhythmic drug with several potentially beneficial actions, and has shown benefit in several small-scale studies. We postulated that this drug might reduce mortality in patients at high risk of death after myocardial infarction because of impaired ventricular function, irrespective of whether they had ventricular arrhythmias.
- Publication
Lancet (London, England), 1997, Vol 349, Issue 9053, p667
- ISSN
0140-6736
- Publication type
Journal Article
- DOI
10.1016/s0140-6736(96)09145-3