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- Title
Randomised trial of nadolol alone or with isosorbide mononitrate for primary prophylaxis of variceal bleeding in cirrhosis. Gruppo-Triveneto per L'ipertensione portale (GTIP)
- Authors
Merkel, C; Marin, R; Enzo, E; Donada, C; Cavallarin, G; Torboli, P; Amodio, P; Sebastianelli, G; Sacerdoti, D; Felder, M; Mazzaro, C; Beltrame, P; Gatta, A
- Abstract
The risk of having a first cirrhosis-associated variceal bleed is lowered by about 50% by beta-blockers. Use of beta-blockers is currently recommended for patients with cirrhosis and oesophageal varices that are at risk of bleeding. We aimed to test the effectiveness of isosorbide mononitrate as an adjunct to the beta-blocker nadolol in the prophylaxis of first variceal bleeding in these patients.
- Publication
Lancet (London, England), 1996, Vol 348, Issue 9043, p1677
- ISSN
0140-6736
- Publication type
Journal Article
- DOI
10.1016/s0140-6736(96)05406-2