We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease.
- Authors
Tang, M X; Jacobs, D; Stern, Y; Marder, K; Schofield, P; Gurland, B; Andrews, H; Mayeux, R
- Abstract
Oestrogen use by postmenopausal women has many health benefits, but findings on the effect of oestrogen in Alzheimer's disease are conflicting. Oestrogen promotes the growth and survival of cholinergic neurons and could decrease cerebral amyloid deposition, both of which may delay the onset or prevent Alzheimer's disease. To investigate whether use of oestrogen during the postmenopausal period affects the risk of Alzheimer's disease, we studied 1124 elderly women who were initially free of Alzheimer's disease, Parkinson's disease, and stroke, and who were taking part in a longitudinal study of ageing and health in a New York City community.
- Publication
Lancet (London, England), 1996, Vol 348, Issue 9025, p429
- ISSN
0140-6736
- Publication type
Journal Article
- DOI
10.1016/S0140-6736(96)03356-9