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Title
Defective acute inflammation in Crohn's disease: a clinical investigation.
Authors
Marks, Daniel J B; Harbord, Marcus W N; MacAllister, Raymond; Rahman, Farooq Z; Young, Jodi; Al-Lazikani, Bissan; Lees, William; Novelli, Marco; Bloom, Stuart; Segal, Anthony W
Abstract
The cause of Crohn's disease has not been mechanistically proven. We tested the hypothesis that the disease is a form of immunodeficiency caused by impaired innate immunity.