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- Title
Safety and efficacy of zinc supplementation for children with HIV-1 infection in South Africa: a randomised double-blind placebo-controlled trial.
- Authors
Bobat, Raziya; Coovadia, Hoosen; Stephen, Cindy; Naidoo, Kimesh L; McKerrow, Neil; Black, Robert E; Moss, William J
- Abstract
Zinc deficiency is associated with impaired immune function and an increased risk of infection. Supplementation can decrease the incidence of diarrhoea and pneumonia in children in resource-poor countries. However, in children with HIV-1 infection, the safety of zinc supplementation is uncertain. We aimed to assess the role of zinc in HIV-1 replication before mass zinc supplementation is recommended in regions of high HIV-1 prevalence.
- Publication
Lancet (London, England), 2005, Vol 366, Issue 9500, p1862
- ISSN
1474-547X
- Publication type
Journal Article
- DOI
10.1016/S0140-6736(05)67756-2