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- Title
Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe.
- Authors
Warny, Michel; Pepin, Jacques; Fang, Aiqi; Killgore, George; Thompson, Angela; Brazier, Jon; Frost, Eric; McDonald, L Clifford
- Abstract
Toxins A and B are the primary virulence factors of Clostridium difficile. Since 2002, an epidemic of C difficile-associated disease with increased morbidity and mortality has been present in Quebec province, Canada. We characterised the dominant strain of this epidemic to determine whether it produces higher amounts of toxins A and B than those produced by non-epidemic strains.
- Publication
Lancet (London, England), 2005, Vol 366, Issue 9491, p1079
- ISSN
1474-547X
- Publication type
Journal Article
- DOI
10.1016/S0140-6736(05)67420-X