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- Title
Long-term effectiveness of potent antiretroviral therapy in preventing AIDS and death: a prospective cohort study.
- Authors
Sterne, Jonathan A C; Hernán, Miguel A; Ledergerber, Bruno; Tilling, Kate; Weber, Rainer; Sendi, Pedram; Rickenbach, Martin; Robins, James M; Egger, Matthias; Swiss HIV Cohort Study
- Abstract
Evidence on the effectiveness of highly active antiretroviral therapy (HAART) for HIV-infected individuals is limited. Most clinical trials examined surrogate endpoints over short periods of follow-up and there has been no placebo-controlled randomised trial of HAART. Estimation of treatment effects in observational studies is problematic, because of confounding by indication. We aimed to use novel methodology to overcome this problem in the Swiss HIV Cohort Study.
- Publication
Lancet (London, England), 2005, Vol 366, Issue 9483, p378
- ISSN
1474-547X
- Publication type
Journal Article
- DOI
10.1016/S0140-6736(05)67022-5