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- Title
Treatment of lymph-node-negative, oestrogen-receptor-positive breast cancer: long-term findings from National Surgical Adjuvant Breast and Bowel Project randomised clinical trials.
- Authors
Fisher, Bernard; Jeong, Jong-Hyeon; Bryant, John; Anderson, Stewart; Dignam, James; Fisher, Edwin R; Wolmark, Norman; National Surgical Adjuvant Breast and Bowel Project randomised clinical trials
- Abstract
Findings from the National Surgical Adjuvant Breast and Bowel Project B-14 and B-20 trials showed that tamoxifen benefited women with oestrogen-receptor-positive tumours and negative axillary nodes, and that chemotherapy plus tamoxifen was more effective than tamoxifen alone. We present long-term findings from those trials and relate them to age, menopausal status, and tumour oestrogen-receptor concentrations. We also discuss the extent of progress made in the treatment of such patients.
- Publication
Lancet (London, England), 2004, Vol 364, Issue 9437, p858
- ISSN
1474-547X
- Publication type
Journal Article
- DOI
10.1016/S0140-6736(04)16981-X