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- Title
In-vivo dominant immune responses in aplastic anaemia: molecular tracking of putatively pathogenetic T-cell clones by TCR beta-CDR3 sequencing.
- Authors
Risitano, Antonio M; Maciejewski, Jaroslaw P; Green, Spencer; Plasilova, Magdalena; Zeng, Weihua; Young, Neal S
- Abstract
Aplastic anaemia is a bone-marrow-failure syndrome characterised by low blood-cell counts and fatty bone marrow. In most cases, no obvious aetiological factor can be identified. However, clinical responses to immunosuppression strongly suggest an immune pathophysiology.
- Publication
Lancet (London, England), 2004, Vol 364, Issue 9431, p355
- ISSN
1474-547X
- Publication type
Journal Article
- DOI
10.1016/S0140-6736(04)16724-X