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- Title
Long-term effects of darusentan on left-ventricular remodelling and clinical outcomes in the EndothelinA Receptor Antagonist Trial in Heart Failure (EARTH): randomised, double-blind, placebo-controlled trial.
- Authors
Anand, Inder; McMurray, John; Cohn, Jay N; Konstam, Marvin A; Notter, Thomas; Quitzau, Kurt; Ruschitzka, Frank; Lüscher, Thomas F; EARTH investigators
- Abstract
Endothelin-receptor blockade provides haemodynamic benefit in experimental and clinical heart failure. We aimed to measure the effects of long-term endothelin-blockade on left-ventricular (LV) remodelling and clinical outcomes in patients with chronic heart failure.
- Publication
Lancet (London, England), 2004, Vol 364, Issue 9431, p347
- ISSN
1474-547X
- Publication type
Journal Article
- DOI
10.1016/S0140-6736(04)16723-8